Prevalence of Viral Hepatitis and its Variable Outcome Among Diabetic Patients

Abstract

Objective:  Evaluation of the clinical and biochemical characteristics among diabetes and non-diabetic individuals suffering from acute viral hepatitis is the focus of this particular research.

Study Design: Prospective/Observational study

Place and Duration: Social Security Teaching Hospital Ferozepur Road Lahore. April, 2021 to Sep, 2021

Methods: This research includes 140 individuals of acute viral hepatitis. Cases in the study ranged in age from 20 to 72 years old. Following signed and informed permission, demographic information, such as a patient's BMI (Body Mass Index), dwelling address, and educational status, were gathered. Patients were divided into two categories. 70 non-diabetic patients were included in group A and 70 diabetic patients with acute viral hepatitis were in group B. In both groups, smoking history was caculated. Both groups of patients had their clinical and biochemical indicators monitored throughout their hospitalization. Analysis was performed by using SPSS 24.0.

Results: In current study males were significantly higher in numbers than females with p value 0.005. In both groups, hepatitis E was the most prevalent cause, followed by B and A. There were considerably greater mean blood bilirubin levels in diabetics than in nondiabetics, as well as lower ALT and albumin levels. Diabetic patients spent an average of 22.5±7.45 days in the hospital compared to 11.4±6.45 days for non-diabetic patients, with a p value of 0.03. Group B had a death rate of 4 (5.7%), due to liver failure, whereas group A had no mortality.

Conclusion: In the present study, we found that diabetes patients with acute viral hepatitis had lower levels of ALT, higher levels of bilirubin, a larger risk of liver failure, and longer hospital admissions than non-diabetic patients with the same condition. Except this death rate in diabetic patients was 5.7%.