Aggressiveness of Breast Carcinoma in Young Pre-Menopausal Patients
DOI:
https://doi.org/10.53350/pjmhs2216478Keywords:
Breast Cancer, Young, Premenopausal, Post-menopausal, Invasive Ductal CarcinomaAbstract
Background: Breast cancer is the most commonly diagnosed malignancy in female population.
Aim: To determine and compare the frequency of aggressiveness of breast cancer in pre and post-menopausal patients.
Study design: Cross sectional study
Place and duration of Study: Department of Histopathology, K.E. Medical University Lahore from 1st January 2016 to 31st December 2018.
Methodology: One hundred and fifty female patients diagnosed with breast cancer to assess the aggressiveness of breast cancer in young - premenopausal patients. Post-Surgical Modified Radical Mastectomy specimens were submitted and evaluated for grade, stage, involved lymph nodes, tumor size and metastasis.
Results: Sixty four percent of the tumors were left sided and the invasive ductal carcinoma was the most dominant histologic type (96%). Ninety two patients were premenopausal while 58 were post-menopausal. Nodal positivity in patients less than 40 years was more pronounced (74.2% versus 56.8%, p=0.029).
Conclusion: Young premenopausal patients represent high risk group for advanced breast cancer.
