Aggressiveness of Breast Carcinoma in Young Pre-Menopausal Patients

Authors

  • Remisha Zahid Shah, Zahid Mehmood Akhtar, Safeena Sarfraz, Syed Hassan Raza Bokhari, Nazia Noor, Attia Lateef

DOI:

https://doi.org/10.53350/pjmhs2216478

Keywords:

Breast Cancer, Young, Premenopausal, Post-menopausal, Invasive Ductal Carcinoma

Abstract

Background: Breast cancer is the most commonly diagnosed malignancy in female population.

Aim: To determine and compare the frequency of aggressiveness of breast cancer in pre and post-menopausal patients.

Study design: Cross sectional study

Place and duration of Study: Department of Histopathology, K.E. Medical University Lahore from 1st January 2016 to 31st December 2018.

Methodology: One hundred and fifty female patients diagnosed with breast cancer to assess the aggressiveness of breast cancer in young - premenopausal patients. Post-Surgical Modified Radical Mastectomy specimens were submitted and evaluated for grade, stage, involved lymph nodes, tumor size and metastasis.

Results: Sixty four percent of the tumors were left sided and the invasive ductal carcinoma was the most dominant histologic type (96%). Ninety two patients were premenopausal while 58 were post-menopausal.  Nodal positivity in patients less than 40 years was more pronounced (74.2% versus 56.8%, p=0.029).

Conclusion: Young premenopausal patients represent high risk group for advanced breast cancer.

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How to Cite

Remisha Zahid Shah, Zahid Mehmood Akhtar, Safeena Sarfraz, Syed Hassan Raza Bokhari, Nazia Noor, Attia Lateef. (2022). Aggressiveness of Breast Carcinoma in Young Pre-Menopausal Patients. Pakistan Journal of Medical & Health Sciences, 16(04), 78. https://doi.org/10.53350/pjmhs2216478

Issue

Vol. 16 No. 04 (2022): Pakistan Journal of Medical & Health Sciences

Section

Articles

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