The Level of Serum Magnesium in the Newly Detected Patients with Glucose Intolerance and its Comparison with Serum Magnesium Levels of Healthy Volunteers Matched for Age and Gender
Yasir Yaqoob, Muhammad Usman, Mubarak Ali Anjum, Muhammad Javaid Iqbal, Bushra Hussain, Aamir Hussain
Background: Hypomagnesaemia is related with resistance to insulin, diabetes mellitus (DM) and its related complications. Then again, patients with diabetes frequently have decreased levels of magnesium. The current examination plans to assess serum magnesium levels in patients with any level of recently analyzed glucose intolerance. For instance, the aim of this study was to correlate serum magnesium levels in people with impaired fasting glucose, impaired glucose tolerance (IGT) or diabetes mellitus and healthycontrol group of individuals of a similar sex was made.
Methods: A case-control study was directed at the Medicine department of Faisalabad Medical University and Allied Hospital,Faisalabad for six-months duration from April 2020 to September2020. Patients with newlydiagnosedglucose intolerance (DM 54, IGT 2) and healthy control group of a comparable age (56 subjects) and gender explicit controls were studied. Serum magnesium levels were estimated altogether study members and contrasted among the control group.
Results:This examination assessed a sum of 56 glucose intolerant patients (cases) and 56 healthy volunteers (controls) of a similar age and sex. There were 24 Males and 32 females in the studied group and 27males and 29 females in the control group. The age range varies from 25 to 60 years of age.The level of serum Mg was normal in 31 individuals in studied group and 44 individuals in the control group, and low in 25 individuals in diseased group and 11 individuals in the control group. The mean levels of Mg in the serum of the patients were lower than in the control group, yet the variance was not significant (p = 0.359). Serum Mg fixations were negatively related with fasting blood glucose (FBG), glucose and glycosylated hemoglobin (HbA1c) following 2 hours (r - 0.527, - 0.560 and - 0.549, individually). Nonetheless, no significant connection was found between serum Mg fixation and irregular blood glucose levels in the control group (r 0.179).
Conclusion: Serum magnesium levels were lower in DM and IGT patients in accordance with age and sex compared withhealthy volunteers, and serum magnesium levels were negatively corresponded with blood glucose levels.
Keywords:Glucose intolerance, Diabetes mellitus,Impaired glucose tolerance,Fasting glycemia disorders and Serum magnesium.