Comparison of the Frequency of Nausea and Vomiting With Dextrose Solution Versus Placebo Solution
Maimoona Zahid, M.Baqir Ali Khan, Tahir Nazeer, Amna Tahir, Shamila A Siddiqui, Liaqat Ali,, Usman Salamat
Background: Nausea and vomiting are stressful common complications of surgeries and causing dissatisfaction of patients.
Aim: To compare the dextrose solution (5% dextrose Ringer Lactate) with placebo (Ringer Lactate) for nausea and vomiting post-operatively in laparoscopic gynecological procedures.
Method:-It was a randomized controlled trial study. 250 patients undergoing elective gynecological procedures under general anesthesia were included and divided into two groups D (dextrose) and P (Placebo) by using lottery method. Each group comprised of 125 patients. Group P received 250 mlringer lactate solution (125 ml/h) and group D received 250 ml 5% dextrose ringer lactate solution (125 ml/h) over 2 hours. General anesthesia was induced with same method in both groups & no prophylactic antiemetic was given. All patient were kept in post-operative area and for pain management 30 mg intravenous ketorolac 12 hourly and inj paracetamol 1g intravenous 8 hourly was given and visual descriptive scale (VDS) scoring was used for assessment of PONV.
Result: In group D 54(43.2%) patients observed PONV and in group P 79(63.2%) observed PONV.
Conclusion: Intravenous 5% dextrose ringer lactate solution reduce the PONV in female patients undergoing for laparoscopic gynecological procedures.
Keywords: Ringer Lactate Solution, 5% Dextrose Ringer Lactate solution, PONV, General Anesthesia