Aim: PPV of contrast
enhanced fluid - attenuated inversion recovery (CE -FLAIR) MRI for diagnosis of
meningitis considering CSF as gold standard
Study Design: It
is a cross-sectional study
Setting & duration: Radiology department,, BVH, Bahawalpur 01-01- 2019 to 30- 06- 2019
Methods: A total of 130 patients having signs & symptoms of meningitis
for last 72 hours with age group 15-50 years were included. MRI was performed
on a 1.5 tesla MR System. The MRI
protocol included the T1W SE sequence, the T2W SE sequence, the T1W sequence
wit h FS, the FLAIR sequence. The CE-FLAIR, T1W sequences wit h MT
and FS were obtained
after administration of intravenous gadobutrol in a dose of 0.1mmo l/kg
body weight. After this, lumbar puncture was done and CSF was sent to the
laboratory for analysis. CE -FLAIR MRI
findings were correlated with CSF report.
Results: All the patients
were subjected first to CE-FLAIR MRI. CE-FLAIR MRI supported the diagnosis of
meningitis in 80 (61.5%) patients. CSF confir med meningitis in 71 (true
positive) cases where as 09 (False Positive) had no meningitis on CSF. PPV of
CE -FLAIR MRI in diagnosis of meningitis was 88.8%.
Conclusion: PPV of CE -FLAIR MRI in diagnosing meningitis
is quit e high.
Keywords: Meningitis, CE -FLAIR MRI