Bacterial sepsis and meningitis continue to be major causes of morbidity and
mortality in newborns, particularly in premature infants. The present study was
undertaken to know the incidence of meningitis in neonates with late onset
Aim: To determine
the frequency of meningitis in neonates with late onset sepsis.
Methods: A descriptive
cross sectional study was conducted in department of pediatrics at sharif
medical city Lahore, from 09-12-2019 to 08-06-2020. One hundred and forty four (144)
neonates with late onset sepsis fulfilling the inclusion criteria were included
in study. Meningitis was confirmed on lumbar puncture and managed as per
hospital protocol. Mean & sd were presented for age, gender, duration of
complain and weight. Frequency and percentage were computed for gender and
age, weight and duration of symptoms in infants with late onset sepsis were
19.50±0.12 days, 3.97±1.17 kg and 4.05±1.98 days. Majority of infants were male
i.e. 63.89% (m:f;1:1.7). Mean wbc count of the infants with late onset sepsis
was 29.78±9.32.majority of infants had less than 75% neutrophils (68.05%),
positive crp (91.67%) and negative blood culture test (52.78%). Frequency of
meningitis in neonates with late onset sepsiswas 34.02%.
frequency of meningitis in neonates with late onset sepsis was high i.e. 34.02%.
Key words: Meningitis; neonates; late onset sepsis