Diagnostic Accuracy of Mri in The Detection of Linear Metastasis in Patients with Pancreatic Carcinoma: A Systamatic Review
Nadia Khalid, Muhammad Jamil Akhtar, Sajid Shaheen Malik, Muhammad Younas, Nawaz Anjum, Iqra Mubeen
Background: Pancreatic cancer is a fatal disease with high mortality rate. Imaging has a significant and decisive interplay in the diagnosis process and in staging of the patients with carcinoma. Thus MRI detection of linear metastasis in patients with pancreatic carcinoma is of great importance.
Objective: The purpose of the study was to find out the diagnostic accuracy of MRI in the detection of linear metastasis in patients with pancreatic carcinoma
Methodology: Systematic literature search was conducted by the help of following search engines: Google scholar, PubMed, NCBI, Medline and Medscape databases from 1999 up to 2020 for names or pancreatic carcinoma, MRI, diagnostic accuracy of MRI in carcinoma, management of motion artifact in MRI, RADAR sequence for motion compensation in MRI. Only those studies were included in this review study which showed the role MRI detection in the patients with pancreatic carcinoma. Total 33 studies were selected and evaluated for the current study. All data extracted from them was further analyzed through meta-analysis.
Results: According to literature MRI detection technique is responsible in the detection of linear metastasis in pancreatic carcinoma. The diagnostic accuracy of the test was high with four out of five studies indicating diagnostic accuracy greater than 90%. Moreover, the sensitivity and specificity of the technique is high i.e. above 0.80 and 0.78 respectively. Thus MRI stands as the significant and accurate marker for the detection of metastasis especially in the case of pancreatic adenocarcinoma.
Conclusion: The reviewed literature indicated that MRI possesses high diagnostic accuracy for detection of pancreatic carcinoma. The sensitivity and specificity of MRI was also high. The results indicated that the use of MRI may help in early detection of Pancreatic Cancer.
Key words: Pancreatic carcinoma, Linear metastasis, Magnetic Resonance Imaging