Nadir Nazir, Mujeeb Ahmed Khan, Faisal, Arsalan Jamil, Zaid Bin Nasir, Adnan Ali Baloch

Comparison of Hemodynamics Effect between Phenylephrine and Ephedrine in Caesarean Section after Spinal Anesthesia

Nadir Nazir, Mujeeb Ahmed Khan, Faisal, Arsalan Jamil, Zaid Bin Nasir, Adnan Ali Baloch



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ABSTRACT

Aim: To compare the frequency of hypotension between phenylephrine and ephedrine groups after spinal anesthesia for cesarean delivery.

Study design: Single-blind randomized clinical study

Place and duration of study: Department of Anesthesia, Pain Management and Surgical ICU Civil Hospital, Karachi from 1st January 2019 to 30th June 2019.

Methodology: All patients with age between 18 to 35 years having weight range 50kg to70kg with American Society of Anesthesiologist (ASA) physical classification of I and II with Singleton Pregnancy assessed on ultrasound and gestational age 37 to 42 weeks assessed on previous dating scan were enrolled.

Results: The mean age was 26.48±3.05 years, mean weight was 60.07±5.10 Kg, mean height 1.53±0.05m and mean BMI was 27.37±5.01 Kg/m2 respectively. Hypotension was found in 13(17.10%) patients. Comparison of hypotension with pehenylephrine and ephedrine shows that frequency of hypotension was found lower (15.4%) in patients who used pehenylephrine as compared to the patients who used ephiderine (p=0.006).

Conclusion: Significant difference was observed in hypotension between phenylephrine and ephedrine groups after spinal anesthesia for cesarean delivery.

Keywords: Hypotension, cesarean delivery, phenylephrine and ephedrine groups, spinal anesthesia



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