Amer Latif, M. Asim Rana, Shahzad Ashraf, M. Afzal Bhatti, Muhammad Javed, Saba Zartash, A. Ali Lashari, M. Mansoor Hafeez

Effectiveness of Rotational Thormboelastometry Algorithm Guided Transfusion Practice in Living Donor Liver

Amer Latif, M. Asim Rana, Shahzad Ashraf, M. Afzal Bhatti, Muhammad Javed, Saba Zartash, A. Ali Lashari, M. Mansoor Hafeez



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ABSTRACT

Background: Liver transplantation is a complicated surgical procedure that involves many complexities such as bleeding and the risk of transfusing blood components.

Aim: To investigate the effect of the Rotational Thormboelastometry (ROTEM) algorithm-based blood or blood product transfusion, in clinical outcome of living donor liver transplant (LDLT) patients.

Study design: Retrospective study

Place and duration of the study: Bahria Town international hospital Lahore from 1st January 2016 to 31st December 2020.

Methodology: Sixty patients of living donor liver transplant were enrolled. They were then divided into two groups as per the approved transfusion protocol. The first group named pre-ROTEM and the second was ROTEM group. Initial biochemical features, blood transfusion and patient outcomes were documented.

Results: The need for large-scale blood transfusion and transfusion-related products were statistically less in ROTEM group as compared to the pre-ROTEM group.

Conclusion: The ROTEM-based algorithms can be used effectively to reduce transfusion of blood components and may increase the chances of early transplant functioning.

Keywords: ROTEM algorithm, Blood transfusion, Liver transplant, ASA guideline, Thromboelastogram, TEG



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