Background: Liver transplantation is a complicated
surgical procedure that involves many complexities such as bleeding and the
risk of transfusing blood components.
Aim: To investigate the effect of the Rotational
Thormboelastometry (ROTEM) algorithm-based blood or blood product transfusion,
in clinical outcome of living donor liver transplant (LDLT) patients.
Study design: Retrospective study
Place and duration of the study: Bahria Town international hospital Lahore
from 1st January 2016 to 31st December 2020.
Methodology: Sixty patients of living donor liver
transplant were enrolled. They were then divided into two groups as per the
approved transfusion protocol. The first group named pre-ROTEM and the second
was ROTEM group. Initial biochemical features, blood transfusion and patient
outcomes were documented.
Results: The need for large-scale blood transfusion
and transfusion-related products were statistically less in ROTEM group as
compared to the pre-ROTEM group.
Conclusion: The ROTEM-based algorithms can be used
effectively to reduce transfusion of blood components and may increase the
chances of early transplant functioning.
Keywords: ROTEM algorithm,
Blood transfusion, Liver transplant, ASA guideline, Thromboelastogram, TEG