Background: Orthopaedic surgeries require sensitive protocol for
prevention of infection pre and post-surgery. Antibiotic-prophylaxis has been
reported for reducing risk of infection in orthopaedic surgeries such as
removal of implants.
Aim: To assess the effect of prophylactic antibiotics in
Place and duration
of study: Dept. of Orthopaedics, Khyber Teaching
Hospital, Peshawar from 1-1-2020 to 31-12- 2020.
Methodology: One hundred and ten patients within 18-75 years were
divided into two groups. Each group had 55 patients. Group 1 were given
prophylactic antibiotics pre-operative as a single dose while group 2 were
given only saline. All patients were admitted for removal of orthopaedic
implants in foot, ankle or leg. Patients 30 days record was observed for any
Results: The mean age of patient was 42.95±10.8 years. Group 1 and
Group 2 had more males than females. There were 10.9% and 9.09% diabetic
patients within group 1 and group 2. The 30 days assessment of post implant
removal orthopaedic surgery showed a decrease of surgical-site infection in
group 1. Surgical-site infection decreased by a rate of
5.4% among patients who were given cefazolin antibiotic.
Conclusion: The effect of prophylactic antibiotic reduces chance of
surgical-site infection in orthopaedic surgery.