Risk Factors and Frequency of Non-Alcoholic Fatty Liver Disease Amongst Non-Obese Individuals
Muhammad Usman, Yasir Yaqoob, Mubarak Ali Anjum, Aamir Hussain, Atiq Ahmad, Muhammad Ayyaz
Introduction: NAFLD(Non-alcoholic fatty liver disease) is a clinically diverse pathological disease described by a histological spectrum varies from modest steatosis to steatohepatitis (NASH), hepatocellular carcinoma (HCC) and cirrhosis.
Aim: To know the pervasiveness of NAFLD and risk factors in non-obese patients.
Methods: This is a cross-sectional examination held in the Gastroenterology, Radiology and Pathology department ofAziz Fatima Medical and Dental College and Aziz Fatima Hospital, Faisalabadfor one-year duration from May 2019 to May 2020. An aggregate of 200 patients took part in the examination.
Results: According to the results, 45 patients have fatty liver and 155 patients didn't have fatty liver. While 148 men and 52females, the mean age is 48.19+ 9.10. Of an aggregate, 19.30% of 200 patients had diabetes. 27.90% dyslipidemia, 23.60% hypertension. Hb in patients with fatty liver and without fatty liver (11.56+1.90 versus 12.50+ 1.09, p <0.001). Absolute serum cholesterol was fundamentally higher in patients with fatty liver versus non fatty liver 233.11+ 20.141versus 180.81+ 23.39 (p <0.001), SGPT 83.24 + 11.10 in fatty liver versus 49.12+ 6.51 in non-fatty liver, SGOT 47.99+ 4.70 in fatty liver versus 40.12+ 4.30 in non-fatty liver in patients with steatosis. We tracked down that 6.24% of patients were HBsAg positive and not any patient was HCV positive.
Conclusion: Metabolic condition, Inactive lifestyle, DM, dyslipidemia are hazard factors for NAFLD in normal individuals. High liver enzymes are the consequence of NAFLD. However, this examination has a few constraints, it will give data about diseases of the liver that happens without hepatitis.
Keywords: dyslipidemia,NAFLD, steatohepatitis and diabetes mellitus.