Aim: To determine the frequency of diastolic dysfunction in preeclamptic women visiting Obstetrics and Gynaecology department at LUMHS Jamshoro.
Methods: This cross-sectional survey was conducted at department of Obstetrics and Gynecology of Liaquat University Hospital, Hyderabad, during the time period of January 2020 to December 2020. All diagnosed preeclamptic at gestational age of > 24 weeks, primigravida with singleton pregnancy between age 20 to 35 years was included in study. Confidentiality was maintained and preclamptic women were referred for echocardiography. The patient with diagnosed gestational hypertension and known cases of eclampsia, diabetes mellitus, any diagnosed renal and heart diseases, patients above 35 years and patients who are not willing to participate in the study were excluded from this study. Analysis was performed by SPSS version 21.
Results: 145 diagnosed preeclamptic pregnant women average age was 26.42±4.14 years. Mostly patients were multiparity in 115(79.31%) cases and belongs to urban areas 76(52.41%) cases. 48(33.10%) were smoker and 35(24.14%) were used tobacco. Frequency of diastolic dysfunction in preeclamptic women was observed in 39.31% (57/145), while in multiparity women 41(28.27%) cases. Diastolic dysfunction was high in rural area 33(22.75%) cases as compare to urban 24(16.55%). It was also high in smoker (p=0.005) as shown in while it was not significant with tobacco users. Rate of diastolic dysfunction in preeclamptic women was high in those women whose family history of disease was observed 37(25.51%) cases.
Conclusion: Preeclampsia still contributes to a predominance concerning maternal mortality and morbidity. Study indicates that in preeclamptic women the frequency of diastolic dysfunction is significant.
Keywords: Diastolic dysfunction, Preeclampsia, Cardiovascular risk.