Study of Association of Serum Concentration of Minerals with Osteoporosis in Postmenopausal Women
Amna Mubeen, Muhammad Arshad, Safdar Ali, Farukh Bashir, Raza Farrukh Shoaib Ahmed
Background: Complete radiological assessment was made that aid in diagnosis of osteoporosis. One of the vital tools in assessment of osteoporosis is via Dual-energy X-ray absorptiometry (DEXA) for screening women that are >45 of age and then final assessment is made on basis of T-scores obtained.
Aim: To estimate and detect serum levels of calcium, phosphorus, magnesium, iron and zinc levels in individuals that are under examination and then comparison of these individuals with individuals in healthy control group.
Place and time of study: DHQ Teaching Hospital Sargodha from January 2019 to March 2020
Methods: Serum calcium, magnesium, iron, zinc and phosphorous were measured and then comparison was made among the candidates with osteoporosis (120) and sound healthy individuals (30). Final assessment of patient with osteoporosis was made by DEXA check.
Results A Comparison was made among postmenopausal women belonging to osteoporosis group and control group and it was found that there was a serious decline in serum levels of calcium in case of postmenopausal women belonging to osteoporosis group. Moreover, there was decline in serum magnesium, phosphorus, zinc and iron levels in candidates with osteoporosis when compared with healthy individuals. There was significant decrease in T-scores observed in postmenopausal women belonging to osteoporosis group when comparison was made with individuals in healthy group.
Conclusion In case of postmenopausal women having osteoporosis there was either low or normal serum levels of calcium, magnesium phosphorus, zinc and iron levels when comparison was made with the controls group. In order to detect osteoporosis in postmenopausal women DEXA is the method of choice with the help of T-scores.
Keywords osteoporosis, calcium, phosphorus, magnesium, iron, zinc, T-scores, DEXA