Aim: To compare
mean operating time, blood loss, post-operative hospital stay and
post-operative complications of thyroid surgery with harmonic scalpel use and
without harmonic scalpel.
Study Design: Randomized controlled trial.
Place and duration of study: Dept of Surgery, DHQ Teaching Hospital, DG Khan from 1stJuly
2017 to 30thJune 2019.
Methodology: One hundred cases of either gender with age more than 15 years
undergoing thyroid surgery of any type were included in this study. The cases
were distributed in two equal groups by simple lottery method. The cases in
group A were managed with conventional hemostasis and those in B with harmonic
and they were assessed for mean operative time, mean blood loss, mean
postoperative hospital stay and number and types of post-operative
mean age in group A and B was 40.22±5.96 vs 38.62±5.65 years. There were 41
(82%) females in group A and 40 (80%) in group B. Mean operative time in group
A and B was 98.16±17.45 vs 84.38±9.34 minutes (p<0.001). Mean blood loss was
76.00±21.40 vs 64.50±16.04 mL (p = 0.003), and mean post-operative hospital
stay was 3.12±0.74 vs 2.48±0.54 days in group A and B respectively with
p=<0.001. Hypocalcemia was observed in 5(10%) vs 4 (8%), Surgical site infections were present in
5(10%) vs 2(4%) and signs of trauma to recurrent laryngeal nerve noted
in 3 (6%) vs 1 (2%) in cases of group A and B.
Conclusion: Harmonic use in surgery of thyroid is significantly better than
conventional hemostasis procedures as it resulted in reduced mean operative
time, less estimated blood loss, less post-operative hospital stay and few
numbers of complications.
Keywords: Thyroid, Harmonic, Hemostasis, Post-operative