AmjadMahmood,, Zardad Khan, SajidRazzaq,ArifMahmood, Nisar Ahmed,WaheedIqbal

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The Likelihood of Helicobacter Pylori presence in pre Chole gall bladder with or without Cholecystitis

AmjadMahmood,, Zardad Khan, SajidRazzaq,ArifMahmood, Nisar Ahmed,WaheedIqbal




Background: Helicobacter pylori is the major pathogen in the etiology of gastric and duodenal ulcers. Hence, there might be a possibility of an underlying H. pylori infestation of gall bladder in causing acute cholecystitis.

Aim: To establish a relation between presence of H pylori and acute cholecystitis

Methodology: It is a case control study, patients who underwent cholecystectomy were classified based on having a normal gall bladder or having one with gallstones/acute cholecystitis into two groups. The tenure of this study was 2010-2019 which carried out at Divisional Head Quarter Teaching Hospital, Mirpur Azad Kashmir. The gall bladders were evaluated for the presence of H. pylori with the help of polymerase chain reaction (PCR). The data was then analyzed and results were compared.

Results: Out of 80 patients studied (44 in case group having acute or chronic cholecystitis, 36 with normal gall bladder), 5 patients from case group whereas 2 patient from control group tested positive for H. pylori on PCR. However this was not statistically significant (p 0.24).

Conclusion: Although H. pylori was found to be present in chronic cholecystitis, however its presence as a causative agent or an influencer could not be proved.

Keywords: Helicobacter pylori, Cholecystectomy, Gall bladder, Cholelithiasis.


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