Umair Arif, Muhammad Rizwan Hafeez, Sibgha Bashir, Adil Mehmood, Rana Aatif Siddique, Saima Nasreen
Pakistan Journal of Medical & Health Sciences




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Examine the Frequency of Acute Renal Failure in Patients with Paraphenylene Diamine Poisoning

Umair Arif, Muhammad Rizwan Hafeez, Sibgha Bashir, Adil Mehmood, Rana Aatif Siddique, Saima Nasreen



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ABSTRACT

 

Aim: To determine the frequency of renal failure in patients presented with paraphenylene diamine (PPD) poisoning.

Study design: Retrospective/Observational

Place and duration: Department of Medicine Shahida Islam Medical & Dental College Lodhran from 1st August 2018 to 31st August 2019.

Methods: Eighty patients of both genders presented with paraphenylene poisoning were enrolled in this study. Patients demographics including age, sex and reasons of ingestion of PPD were recorded after taking written consent from patients/attendants. Clinical presentation including sign and symptoms were recorded. Frequency of acute renal failure was examined by serum creatinine mg/dl.

Results: Sixty two (77.5%) were females while 18(22.5%) were males. The mean age was 24.32±6.54 years. Suicide was the most common reason for poisoning of PPD found in 76 (95%) cases. Cervicofacial edema was the commonest symptom found in 74(92.5%) patients. Acute renal failure was observed in 65 (81.25%) patients. From 65 ac renal failure patients 60(92.31%) were recovered after treatment while 5 (7.69%) had residual renal damage.

Conclusion: The frequency of acute renal failure in paraphenylene diamine poisoning patients was very high, however quick medical treatment helps to reduce the morbidity and mortality.

Keywords: Paraphenylene diamine poisoning, Acute renal failure


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