Samreen Ashraf, Muhammad Zeeshan Khan, Fariha Ahmed Khan, Nighat Sultana, Muhammad Sarwar, Afsheen Batool Raza
Pakistan Journal of Medical & Health Sciences




Peer Reviewed

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Spectrum of bacterial infections among severely acute malnourished children in a tertiary care center

Samreen Ashraf, Muhammad Zeeshan Khan, Fariha Ahmed Khan, Nighat Sultana, Muhammad Sarwar, Afsheen Batool Raza



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ABSTRACT

 

Aims: To determine common bacterial infections in severely malnourished children and its effect on duration of hospital stay.

Methods: It was a cross sectional observational study held at pediatric medical unit of The Children’s Hospital and the Institute of Child Health, Lahore from March 2018 to February 2019. 150 children between 6 months to 5 years of age having severe acute malnutrition (SAM) with positive cultures for bacterial infection included in study. Majority of the children were between 13 to 24 months. Patients were enrolled according to inclusion criteria. Children with chronic liver disease, chronic kidney disease, malignancy and cardiac problem were excluded. Cultures were taken on admission and 48 hours after admission. All positive bacterial cultures were recorded.

Results: Bacteremia was seen in 35 (24%) of the 150 study subjects. There were a total of 8 bacterial isolates. S. aureus (2%) was common among gram positive isolates whereas E. Coli was the most common among Gram negative isolates followed by Klebsiella (7%) and pseudomonas (6%) respectively. 70 patients (46%) were admitted for nutritional rehabilitation with mild symptoms but still had bacteremia (27%).

Conclusion: High index of suspicion of infection should be considered in SAM patients. Early initiation of appropriate antibiotics according to common pathogen may help in reducing the mortality and morbidity.

Key words: Bacteremia, Severe acute malnutrition, Antibiotics



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