Aim: To examine
the diagnostic accuracy of ultrasound for diagnosing malignant thyroid nodules
and its management taking fine needle aspiration cytology as a gold standard.
Study Design: Cross-sectional study
Place and Duration of Study: Department of Diagnostic Radiology and ENT and Head & Neck Surgery
Civil Hospital Quetta and Yaseen Hospital Quetta from 1st March 2017
to 31st December 2019
hundred and twenty patients of both genders with ages 20 to 65 years clinically
diagnosed to have thyroid nodules were included in this study. Patient’s
detailed demographics were recorded after taking informed written consent. Ultrasound
imaging was performed to all the patients and compared the findings with
ultrasound guided. Sensitivity, specificity, positive predictive value (PPV),
negative predictive value (NPV) and diagnostic accuracy of ultrasound were
examined. Total thyroidectomy was performed and follow-up was taken at 1 year
post-operatively to examine the recurrence rate.
(75%) were females while 30 (25%) were males with mean age 39.14±12.85 years.
29 (24.17%) patients had malignant and 91 (75.83%) had benign thyroid nodules
by ultrasound while on FNAC 30 (25%) patients had malignant and 92 (76.67%) had
benign nodules. Sensitivity, specificity, PPV, NPV and diagnostic accuracy of
ultrasound compare to FNAC were 86.67%, 96.67%, 89.66%, 95.60% and 94.17%
respectively. Total thyroidectomy was performed to all the patients who had
positive findings of malignancy. Out of 30 patients 25 (83.33%) were females
while 5 (16.67%) were males with mean age 40.25±13.57 years. At 1 year
follow-up none of patients had recurrence.
Conclusion: Ultrasound plays an important role for diagnosing malignant thyroid
nodules with high diagnostic accuracy rate. It is very helpful tool for making
decision for the management of thyroid nodules.
Nodules, Ultrasound, Fine needle aspiration cytology, Thyroidectomy