Muhammad Azam, Muhammad Rashid, Muhammad Younis, TanveerAkhtar Butt
Pakistan Journal of Medical & Health Sciences




Peer Reviewed

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Comparison of Thiopental Sodium and Lidocaine to Prevent the Pain Associated with Propofol Injection

Muhammad Azam, Muhammad Rashid, Muhammad Younis, TanveerAkhtar Butt



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ABSTRACT

 

Aim: To determine whether the pretreatment with thiopental sodium 0,5mg is better than lidocaine 40mg to prevent the pain associated with propofol injection.

Study Design: Randomized control trial.

Place & Duration: Department of Anesthesiology, Central Park Medical College and Hospital Lahore from 1st January 2019 to 30th June 2019.

Methods: One hundred cases of ASA I-II aged 18-20 years old for elective surgery under general anesthesia were included. They were divided in two groups; group A and group B, each comprised 50 patients. At the time of induction of general anesthesia, group A was pretreated with injection thiopental sodium 0,5mg /kg and group B was with injection lidocaine 40mg after applying the tourniquet. All study drugs were made into 2ml with normal saline. The patient were observed and asked for pain after every 5-10 sec during the induction of propofol injection.

Results: Patients in group A reported a significantly less pain as compared to group B.

Conclusion: Using the thiopental sodium 0,5mg/kg before induction with propofol injection is better and safe to prevent the pain caused by propofol injection is better than lidocaine 40mg in elective surgery.

Keyword: Propofol, Thiopental sodium, Lidocaine



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