Background: Hypertension is the commonest medical disorder encountered
during pregnancy with a reported frequency of 9.8% in general population.
Though the exact cause is not yet known, a lot of factors have been found
associated with pregnancy induced hypertension. One such factor is maternal
serum dyslipidemia. However, in most of the previous studies, there was doubt
about the possible association between maternal serum dyslipidemia and
pregnancy induced hypertension.
Aim: To determine the frequency of pregnancy
induced hypertension among pregnant women visiting a tertiary care facility and
to compare the serum lipid profile in normotensive and hypertensive pregnant
Methods: This was a descriptive cross-sectional study conducted at the Obstetrics
and Gynaecology department of Lahore Medical and Dental college and Ghurki
trust teaching hospital, Lahore, between 1/01/2017 to 30/06/2017. 200 patients who
presented in the outpatient’s department and fulfilledthe inclusion
criteriawere included in this study after taking an informed written consent. Known
hypertensive patients and those with underlying vascular disease were excluded.
Results: The results showed that
23(11.5%) patients were hypertensive while majority (88.5%) of the patients
were normotensive. There was significant difference among the two groups in
terms of serum triglycerides (163.70±15.11 vs. 108.59±7.84 mg/dl; p=0.000),
total cholesterol (192.83±13.13 vs. 148.89±5.821 mg/dl; p=.001), LDL
(133.40±10.10 vs. 73.56±2.26 mg/dl; p=0.000), VLDL (113.55±9.01 vs. 48.63±2.72
mg/dl; p=0.000) and HDL (37.41±1.85 vs. 52.54±1.63 mg/dl; p=.033).
induced hypertension is quite frequent among pregnant women and there is
significant association between maternal serum dyslipidemia (raised
triglycerides, total cholesterol, LDL, VLDL and reduced HDL) and pregnancy
Keywords: Pregnancy Induced
Hypertension, Lipid Profile, Cholesterol