Zia ul Islam, Hassan Ali, Sumaira Nighat, Hammad Ahmad Saqib, Atqa Firdous, Neelum Malik, M. M. Khan
Pakistan Journal of Medical & Health Sciences




Peer Reviewed

Previous Published Issues


Diagnostic Accuracy of MRI Findings in Diagnosing Spinal TB Taking Histopathology as Gold Standard

Zia ul Islam, Hassan Ali, Sumaira Nighat, Hammad Ahmad Saqib, Atqa Firdous, Neelum Malik, M. M. Khan



389




ABSTRACT

Aim: To determine the accuracy of magnetic resonance imaging (MRI) for assessment and diagnosis of spinal TB in suspected patients.

Methods: This validation study included 80 suspected cases of spinal TB (Positive Tuberculin skin test (PPD), ESR>100) having age 18 to 65 years, who were referred for MRI evaluation. The study was conducted the radiology department of Ibne -Sienna hospital from January 2020 to September-2020. Initially in all patients, MRI evaluation was done. After that biopsy specimens were took under US guidance and sent for histopathology evaluation.

Results: Mean age of study cases was 50 45.1±9.6 years. Majority, 50(62.5%) patients were men and 30(37.5%) were women. Out of 80 suspected patients, spinal TB was diagnosed in 67 cases on MRI, while on histopathology spinal TB was diagnosed in 64 cases. In remaining 13 patients, 2 patients were diagnosed on spinal TB on histopathology. The sensitivity of MRI was 97.0%, specificity 78.6%, PPV 95.5% and NPV 84.6%.

Conclusion: Accuracy of MRI for diagnosing spinal TB is quite high. So MRI should be used as first-line imaging modality in these patients and histopathology should be advised in those patients having strong suspicion of other underlying diseases in these patients.

Keywords: Magnetic resonance imaging (MRI), Spinal Tuberculosis.



Copyright © Pakistan Journal of Medical & Health Sciences 2021. All rights reserved!