Saima Naz Mohsin, Amir Razi, Jawad Hussain Qamber, Uzma Nasim Sidiqqui, Faisal Hashmi

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Prevalence and Associated Factors of Albuminuria in Apparently Healthy Individuals in Lahore

Saima Naz Mohsin, Amir Razi, Jawad Hussain Qamber, Uzma Nasim Sidiqqui, Faisal Hashmi



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ABSTRACT

 

Aim: To determine the prevalence of albuminuria in apparently healthy individuals of Lahore and find the association of risk factors with albuminuria

Study design: Cross sectional survey.

Place and duration of study: PHRC Research Centre NHRC, Shaikh Zayed Medical Complex, Lahore from 1st January 2019 to 29th February 2020

Methodology: Survey was conducted after the ethical clearance from IRB of SZMC and permission from TMOs, Heads of union councils and commandant of DHA in Lahore. Two thousand and forty two subjects fulfilling the inclusion criteria were enrolled and interviewed to fill-up the questionnaire. All subjects were tested for Albumin: Creatinine ratio in morning spot urine sample.

Results: Overall prevalence of albuminuria was found to be 20.57%. Factors like old age (24.1% with p=0.004), obesity (26.6% with p< 0.0001) showed significant association with the presence of albuminuria. A positive family history of chronic kidney disease, diabetes and hypertension were also found to be strongly associated with albuminuria (p-values=0.0001, 0.002 and 0.002, respectively).

Conclusion: All at risk healthy individuals should be screened for albuminuria for early diagnosis of chronic kidney disease.

Keywords: Albuminuria, Microalbuminuria, Chronic kidney disease, Renal impairment, Albumin creatinine ratio



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