Serum β-hCG Levels as a Predictive Marker for Gestational Hypertension: A Cross-Sectional Study at Major Shabbir Sharif Hospital, Kunjah, Pakistan

Abstract

Background: Pregnancy-induced hypertension (PIH) is a dangerous obstetric condition that can harm the mother and unborn child. The aim of this study was to examine the relationship between β-hCG levels in the circulation and the risk of developing polycystic ovarian syndrome (PIH). The study also assessed β-hCG's potential as an early marker for PIH.

Materials and Methods: Between November 2021 and December 2022, the Major Shabbir Sharif Hospital in Kunjah, Pakistan, conducted a cross-sectional study. Research was done between 2021 and 2015. The study involved 100 pregnant women aged 20–40 and 14–19 weeks along. Participants were categorised by age, socioeconomic position, and occupation. This classified participants. After the measurements and analysis, serum β-hCG and blood pressure levels were measured.

Results: With 27.6 participants, the age range was covered. Sixty-one percent had normal blood pressure, whereas thirty-nine percent were at risk for mild, moderate, or severe peripheral arterial hypertension (PIH). The rest of the study participants had normal blood pressure. Higher levels of β-hCG were linked to more severe premenstrual hypertension (PIH). PIH patients had higher pedestal oedema and proteinuria. Additionally, elevated β-hCG levels were connected to similar symptoms.

Conclusion: Elevated β-hCG levels may aid in early management and predict polycystic ovarian syndrome (PIH). Including β-hCG monitoring in prenatal care may improve results for both mother and baby.

Keywords: Pregnancy-Induced Hypertension, β-hCG, Early Prediction, Maternal Health, Fetal Outcomes.