Role of Antibiotic Prophylaxis and GCSF Support in Preventing Systemic Anticancer Therapy-Associated Toxicities in HIV Infected Cancer Patients: A Case Series

Abstract

This is a case series report of five HIV-positive patients diagnosed with non-AIDS-defining cancer who received the combination of ART and chemotherapy. There is an increasing incidence of non-AIDS-defining cancers, such as breast cancer, lung cancer, hepatocellular carcinoma, prostate cancer, colorectal cancer, and Hodgkin’s lymphoma. The purpose of this study is to see the impact of appropriate antibiotics prophylaxis and G-CSF Support in preventing the toxicities associated with systemic anti-cancer therapy (SACT) in HIV Patients.

Keywords: Human Immunodeficiency Virus, Acquired Immune Deficiency Syndrome, Anti-Retroviral Therapy, AIDS Defining Cancer, systemic anti-cancer therapy (SACT), Non-Aids Defining Cancer.