Analysis of E-Cadherin Expression in Patients with Esophageal Squamous Cell Carcinoma

Authors

  • Muhammad Ali Soomro, Sidrah, Suresh Kumar, Aneela Faisal Memon, Azhar Ali, Kiran Memon, Kiran, Aamir Ramzan

DOI:

https://doi.org/10.53350/pjmhs2023174412

Abstract

Objectives: Esophageal Squamous Cell Carcinoma is a common, deadly cancer. E-Cadherin expression in cancer was investigated along with its relation to parameters like age, gender, differentiation, and mortality.

Methodology: A 100-sample descriptive cross-sectional study utilising open EPI software with a 95% confidential interval was obtained. Data was evaluated by SPSS 23.0.

Results: E-Cadherin had a negative IRS (immune-reactive score) in 69% of samples, mild in 27%, and moderate in 4%. Chi-square test showed no association between E-cadherin immune-reactive score and the parameters considered. (>P=0.05)

Conclusion: This study found that patients with carcinoma express less E-Cadherin but its expression in Esophageal Squamous Cell Carcinoma patients is unrelated to the parameters considered.

Keyword: Esophageal Squamous Cell Carcinoma, Immuno-Histochemistry, Haematoxylin, Eosin, E-Cadherin.

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How to Cite

Muhammad Ali Soomro, Sidrah, Suresh Kumar, Aneela Faisal Memon, Azhar Ali, Kiran Memon, Kiran, Aamir Ramzan. (2023). Analysis of E-Cadherin Expression in Patients with Esophageal Squamous Cell Carcinoma. Pakistan Journal of Medical & Health Sciences, 17(04), 412. https://doi.org/10.53350/pjmhs2023174412

Issue

Vol. 17 No. 04 (2023): Pakistan Journal of Medical & Health Sciences

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Articles

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