Use of Antenatal Steroids Treatment to Reduce Neonatal Respiratory Morbidity Prior to Cesarean Section in Preterm Birth

Authors

  • Ammar Noor, Wajeeha Rafi, Hafiz Muhammad Hashim Khan, Tayyab Arif Butt, Muhammad Inam Ul Haq, Muhammad Mohsin Bajwa

DOI:

https://doi.org/10.53350/pjmhs22165499

Keywords:

Antenatal corticosteroids, Elective cesarean section, Neonatal respiratory morbidity.

Abstract

Objective: To compare the rate of neonatal respiratory morbidity between individuals who received prenatal corticosteroids before to caesarean delivery at 34-37 weeks and those who did not.

Patients and Methods: A total of 150 patients who presented with preterm labour having gestational age between 34-37 weeks and no neonatal congenital anomaly on anomaly scan were recruited from June-2021 to December-2021 from the gynecology unit of Nishtar Hospital Multan. Women divided into two groups. Group A; in these patients intramuscular dexamethasone (12 mg) was given in 2 doses 12 hours apart. Group B (Control group): in these patients no drug was given as a prophylaxis again neonatal respiratory morbidity. After delivery, each neonate was monitored for 24 hours after delivery to determine the respiratory morbidity.

Results: Mean age of patients was 31.19±5.02 years. Mean gestational age was 35.66±1.10 weeks with range of 34-37 weeks. There were 78 (52.0%) patients who were prima-gravida and remaining 72 (48.0%) were Multi-gravida. There were 14 (9.3%) patients who were having previous abortion history. Respiratory morbidity was diagnosed in only 2 (2.7%) neonates in group A and in 07 (9.3%) neonates in group B (p-value 0.08)

Conclusion: Prenatal corticosteroid therapy prior to elective caesarean section at 34–37 weeks of gestation significantly reduces neonatal respiratory morbidity.

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How to Cite

Ammar Noor, Wajeeha Rafi, Hafiz Muhammad Hashim Khan, Tayyab Arif Butt, Muhammad Inam Ul Haq, Muhammad Mohsin Bajwa. (2022). Use of Antenatal Steroids Treatment to Reduce Neonatal Respiratory Morbidity Prior to Cesarean Section in Preterm Birth. Pakistan Journal of Medical & Health Sciences, 16(05), 499. https://doi.org/10.53350/pjmhs22165499