Prevalence of Potent Drug Interactions in Malarial Patients and its Related Physiology

Abstract

Objective: To find the prevalence of drug-drug interaction in malarial patients.

Study Design: Retrospective study

Place and Duration of Study: Department of Pharmacology, Watim Medical & Dental College, Islamabad Rawat from 1^ST May 2021 to 30^th November 2021.

Methodology: Eighty malarial patients were enrolled. The patients were divided into two groups with 40 patients in each group. Group A had patients only suffering from malaria while Group B was malarial patients who were also having co-morbidity. There drug-drug interaction was analyzed and prevalence determined.

Results: The mean age was 22.1±3.2 years. There was greater than 5 days’ hospital stay in 62.5% cases with malaria in addition to co-morbidities. The drug interaction was present in 8 cases out of 40 in group A while 20 in group B.

Conclusion: The potential of drug-drug interaction is as high as 35% in malarial patients