Muhammad Sarwar Khan, Kiran Aamir, Aamir Ramzan, Aasma Naz, Khalil Ahmed Memon, Irfan Ahmed

Bleeding Disorders among women Presenting with Menorrhagia at Tertiary Care Hospital

Muhammad Sarwar Khan, Kiran Aamir, Aamir Ramzan, Aasma Naz, Khalil Ahmed Memon, Irfan Ahmed



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ABSTRACT

Objective: To study the spectrum of bleeding disorders among women, presenting to the study setting with complaints of menorrhagia.

Methodology: This observational cross-sectional study was conducted up on 121 women, during a period of 6 months, who were approached via non-probability, consecutive sampling, presenting to the Dept. of Gyneacology & Pathology – Liaquat University Hospital, Hyderabad with menorrhagia. Data obtained from patient interviews and laboratory investigations were recorded into a self-structured questionnaire after taking written informed consent. The data obtained was analyzed using SPSS v. 21.0.

Results: The mean age of the women was 28.13 years (±5.21 SD). Among the underlying hemostatic pathologies, VWD was the most common i.e. 21 (65.6%), followed by other platelet dysfunctions (Glanzman Thrombasthenia (n=5, 15.6%) and Berard Soulier Syndrome i.e. n=3, 9.4%) comprised the second most common finding. A cause of hemostatic pathology among a minority of patients remained unidentified i.e. n=3 (9.4%).

Conclusion: Keeping in view of hemostatic defects, the study concludes that VWD is the commonest bleeding disorder among women presenting with menorrhagia. A routine screening of females with menorrhagia on their initial contact with the hospital can save years of suffering and lead to early management and probable recovery.

Keywords: Von Willebrand Disease, Hemostatic Dysfunction, Bleeding Disorders, Platelet Dysfunction, Menorrhagia & Bleeding Complaints among Women



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