Objective: The aim of this study is to compare the ICU stay and mortality in vaccinated and nonvaccinated

covid-19 patients.

Study Design: A Retrospective/ Comparative study

Place and Duration: The study was conducted in Medicine department of Fauji Foundation Hospital Rawalpindi,

duration of six months from October 2020 to March 2021.

Methods: Total 120 patients of both genders had coronavirus disease were presented in this study. Patients were

aged between 22-80 years. Demographical details of patients including age, sex, body mass index, residency and

socio-economic status were recorded after taking informed written consent. Patients were admitted in COVID 19

ward. Chest X-rays of both groups were taken. There were 50 vaccinated patients in group I and 70 nonvaccinated

patients in group II. Co-morbidities among both groups were assessed. Recovery and outcomes

among both groups were calculated in terms of mortality and reduction in severity of disease. Complete data was

analyzed by SPSS 24.0 version.

Results: There were 80 (66.7%) patients were males (35 in group I and 45 in group II) and 40 (33.3%) were

females (15 in group I and 25 in group II). Mean age of the vaccinated patients was 46.21 ±9.67 years with mean

BMI 32.12 ±6.33 kg/m2 and in group II mean age was 45.13 ±21.54 years with mean BMI 33.11±11.37 kg/m2. 34

(68%) were educated in group I and in group II 35 (50%) patients were literate. Severity of disease among nonvaccinated

patients was high found in 55 (78.6%) cases as compared to vaccinated cases 17 (34%). Comorbidities

were diabetes mellitus, hypertension, ischaemic heart and chronic lung disease. Most of the patients

90 (75%) had bilateral lung involvement and interstitial infiltrates 105 (87.5%). Fever, cough and dyspnea were

the most common symptom found in both groups. Recovery among patients of group I was greater 40 (80%) as

compared to non-vaccinated 27 (38.6%). Frequency of poor outcomes hospitalization 9 (12.9%), ICU admission

11 (15.8%) and mortality 23 (32.9%) among non-vaccinated patients were significantly higher as compared to

vaccinated patients in which hospitalization 2 (4%), ICU admission 3 (6%) and mortality was found in 5 (10%)

cases.

Conclusion: According to the findings of this study, vaccination against coronavirus disease is both efficacious

and beneficial in reducing disease severity. Except for this, immunization can reduce the frequency of poor

outcomes (hospitalization, ICU admission, and mortality), and individuals should be made aware of the

importance of becoming vaccinated as soon as possible.

Keywords: COVID 19, Vaccination, Pandemic, Mortality