Objective: To compare the outcome of nonsteroidal anti-inflammatory drugs versus muscle relaxant for the adult

patients with temporomandibular dysfunction.

Material and Methods: A total of 120 patients of TMD of both genders and aged 20 to 50 years were enrolled.

Subjects in group A were given oral non-steroidal anti-inflammatory drug (ibuprofen 400mg) twice a day. Subject

of group B were given one oral diazepam (5 mg) tablet daily. At baseline, pain score was assessed.

Results: Comparison of mean post-treatment visual analog scale (VAS) pain scores in both study groups showed

that mean post-treatment VAS pain score was significantly less in Group A in comparison to Group-B (2.15+1.12

vs. 3.20+1.04, p<0.001).

Conclusion: Nonsteroidal anti-inflammatory drugs (ibuprofen) was found to have significantly better reduction in

pain scores in comparison to muscle relaxant (diazepam) among adult patients with temporomandibular

dysfunction.

Keywords: Ibuprofen, diazepam, temporomandibular dysfunction.