Aim: To investigate the causes of incidence of gallstones in case of children and response to treatment via ursodeoxycholic acid

(UDCA) Methods: 42 children suffering from cholelithiasis were selected, and gallstones were scanned using ultrasonography.

The findings of scan of these children were recorded in Performa. Study duration

18 months Children's Hospital and the Institute of Child Health Lahore

Results: The most common risk factor in case of incidence of gall stones was a family history. By the aid of UDCA treatment

many children showed positive response especially in first six months where as children suffering from hemolytic diseases were

failed to depict any response to UDCA. Treatment

Conclusion: UDCA treatment proved to be beneficial to patients with asymptomatic profile before surgery in case of children

suffering from cholelithiasis and having no hemolytic pathologies.

Keywords: Cholecystectomy, Gallstone, Ursodeoxycholic acid.