Objective: To determine the frequency of causes of space occupying lesions of brain in patients admitted in Neurosurgery ward PUMHS Nawabshah over a period of one year

Methodology: This descriptive case-series study took place at department of Neurosurgery of Peoples University of Medical and Health Sciences, for Women Shaheed Benazirabad. Study duration was one year from July 2019 to June 2020. All the patients with space-occupying lesion of brain either of gender were enrolled in this study. All study subjects were assessed for the causes of space-occupying lesion. Data was collected vis study proforma and analysis of the data was done by using SPSS version 20.

Results: A total of 80 patients were selected, their mean age was 31.76 years and females were in majority 66%, with female to male ratio of 1.96:1. Glioma was found in 23% cases which was highest among all type of lesion followed by abscess 10%. Supratentorial was observed in 73% patients which was highest among all site of lesion followed by third ventricular & Infratentorial 10% each.

Conclusion: The increased prevalence of infectious lesions can be linked to our population's low socioeconomic level and inadequate hygienic conditions. The rate of metastasis was found to be lower than previously reported. This might be attributed to cases not being referred following a metastatic lesion has been diagnosed. For early detection of brain tumours, advanced diagnostic equipment such as CT scans and MRI are desirable.

Keywords: SOL, Central Nervous System, Metastases