Relation between Chronic Obstructive Pulmonary Disease and Peripheral Arterial Disease among Construction Workers
U. Sivakumar, Rinku Garg, Sunita Nighute
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ABSTRACT
Introduction: PAD was asymptomatic in a large
proportion of COPD patients and was associated with more severe lung disease
than in COPD subjects without PAD.
Materials
and Methods: This was a Cross-sectional study conducted at
Department of Physiology, Santosh Medical College diagnosed with COPD using
Spirometry was recruited for the study with a Sample size of 130 patients.
Results: The characteristics of the
population for follow-up (n=130) are presented in table 1. The mean Mean±sd was
51.73±6.1 years. The prevalence of never smokers was 21.5%,
former smokers were 51.5% and current smokers were 26.9%. In total, 41 out of
130 individuals (31.5%) had PAD based on an ABI of less than 0.6. A
statistically significant association was found between COPD and newly
diagnosed PAD during follow-up. The association between COPD and incident PAD
was stronger (adjusted OR 1.91, 95% CI 1.14–3.21). Stratified analysis by
smoking status revealed that the overall association between COPD and newly
developed PAD was driven by the ever smoker group.
Conclusion:
Subjects
with COPD have a higher risk of developing PAD. People with both COPD and PAD
have a substantially increased risk of death. Consequently, early detection of
PAD and preventive actions in people with COPD should receive more attention in
clinical respiratory care.
Keywords: Peripheral Arterial Disease, Chronic Obstructive
Pulmonary Disease, Ankle-brachial index.