Frequency of Vitamin B12 Deficiency in Pregnant Women with Gestational Diabetes Mellitus
Shazia Jamil, Naveed Mahmood, Israr-ul-Haque, Rabiah Haque, Muhammad Imran-ul-Hasan, Maheen Anwaar
2753
ABSTRACT
Objective: To determine the prevalence of vitamin B-12 deficiency in pregnant women
with gestational diabetes mellitus.
Study Design: Retrospective study
Place and Duration of Study: Department of Medicine, OMC Hospital, Jail Road Lahore
from January, 2020 to December, 2020.
Methods: Two
hundred and thirty pregnant females were enrolled age between 18-45 years.
Detailed demographics of enrolled cases age, gestational age, gravidity and
body mass index were recorded after taking informed written consent. Among 230
cases, 100 women were non GDM (group I) and 130 had gestational diabetes
mellitus (group II). Blood samples were taken from all the patients for
measuring vitamin B12 status. Vitamin B12 was defined as <300 pg/ml.
Results: Mean age of the patients in group I was
31.64±7.45 years with mean BMI 25.88±8.65 kg/m2 while mean age among
GDM group was 34.55±5.71 years with mean BMI 27.36±9.44 kg/m2. Mean
gestational age in group I was 33.72±4.21 weeks and in group II 35.08±9.27
weeks. In group I 20 (20%) had vitamin B12 deficiency and in group II rate
ofvitamin B12 deficiency was high among 90 (69.2%) cases. We found a
significantly relation between vitamin B12 and GDM with p value <0.0007.
Conclusion: The prevalence of vitamin B-12 deficiency among pregnant women of
gestational diabetes mellitus was significantly high as compared to normal
pregnant women.
Keywords:
Pregnant Women, Gestational
Diabetes Mellitus, Vitamin B12 deficiency