Abstract

Aim: To study Pseudomonas aeruginosa antibiotic sensitivity, resistance, and the biofilm capacity from patients that have contact-lens-associated diseases.

Methods: Total 159 specimens somewhat from four central hospitals within Baghdad City collected from infection which associated with eyes through January 2018 to July 2018, 115 of such specimens reported here that presence of bacteria had been positive. Amongst these, 42 (36.5%) seemed to be positive whereas 73 (63.5%) constituted negative gram stain. Pseudomonas aeruginosa 54 (46.9%), Staphylococcus spp. 25 (21.7%), Acinetobacter spp. 12 (10.5%), Streptococcus spp. 9(7.8%), Micrococcus spp. 7 (6.2%), Serratia marcesens 4 (3.5%), E coli 3 (2.6%) and Bacillus spp. 1 (0.8%).

Results: The resistance to antibiotics was for Ciprofloxacin (90.7%), Cefazoline (88.8%), Ofloxacin (87.03%), Gentamcin (83.3%), Cefepime (77.7%) as well as towards Ceftriaxone (75.9%) were recorded. High imipenem resistance (64,8%) has been followed by neomycin (62,9%), ampicillin – Sulbactam also Nitrofurantoin (61,1%) as well as ceftazidime (53,7%), and less resistance towards Tobromycin (33.3 %), and 38.8% toward Amikacin. Capacity with biofilm formation had also been observed throughout 96.3% and 3.7% of non-biofilm development.

Conclusions: Scientific understanding about biofilm development as well as resistance to antibiotics contribute to the discovery of other innovative goals toward Pseudomonas eye infection therapy. These typically continue to exist even after its long-term usage of different antibiotic treatment. Its capacity about progress throughout a biofilm improves their own opportunities of protecting themselves against host protection mechanisms, antimicrobial remedy or otherwise biocidal products.

Keywords: Biofilm, Pseudomonas aeruginosa, ocular infection, Baghdad