Laila Khan, Nasreen Aman, Aeishabegum


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Abstract


Objective:Toexamine the diagnostic accuracy of MRI for diagnosing carcinoma of cervix taking histopathology as gold standard.

Study Design:Retrospective

Place and Duration: Study was carried out at department of Radiology, MTI Lady Reading Hospital, Peshawar for duration of one year from June 2018 to June 2019.

Methods:Sixty women clinically diagnosed to have carcinoma of cervix were included. After taking written consent, patients’ detailed demographics were recorded. All the patients underwent MRI of pelvis to detect the malignancy. Biopsy specimen were taken and sent to laboratory for histopathological examination. Sensitivity, specificity, PPV, NPV and diagnostic accuracy of MRI were examined. Data was analyzed by SPSS 24.0.

Results:Mean age of patients was 48.46±10.62 years. Hypertension was the commonest co-morbidity in 14 (23.33%) patients. Post-menopausal bleeding was the commonest clinical presentation found in 25 (41.66%) patientsfollowed by irregular vaginal bleeding in 21 (35%) patients.By MRI 45 (75%) patients found to have malignancy and 15 (25%) had negative findings. The sensitivity, specificity, PPV, NPV and diagnostic accuracy of MRI were 94.62%, 92.59%, 97.78%, 87.33% and 94.17% respectively.

Conclusion:Magnetic resonance imaging is very useful diagnostic tool for diagnosing carcinoma of cervix and should be used as an alternate to histopathological examination.

Keywords:Cervix Carcinoma, Magnetic Resonance Imaging, Accuracy.



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