Abstract

Objective: To compare the efficacy of prophylactic placement of pancreatic duct stenting versus no stenting during ERCP to prevent post ERCP pancreatitis.

Study Design: Randomized controlled Trial

Place and Duration: Conducted in Gastroenterology department at Shaikh Zayed Hospital Lahore, for duration of 6 months from November 2019 to April 2020.

Methodology: Two hundred patients of both genders with ages 18 to 60 years underwent ERCP were enrolled in this study. Patients were randomized into two groups. Group A (100) were those patients who had prophylactic stent and group B (100) was the cases who did not have prophylactic stent during ERCP. Serum amylase was sent within 24 hours. Efficacy was evaluated if patient did not develop pancreatitis after ERCP assessed at 24 hour after ERCP.All data was entered into SPSS version 20 and analyzed.

Results: Mean age of 34.67±9.08 years (range=2-0-59). Majority of the patients were male77.5%while female cases were 45(22.5%). The efficacy in terms of absence of pancreatitis because of the procedure was noted in 164(82%) overall ERCP cases. Patients in group A who had prophylactic stenting did not develop pancreatitis after ECRP within 24 hour while no pancreatitis after 24 hour of ECRP was noted in 74(74%) of cases in group B in which no stenting was carried out(p-value=0.003) and this difference was statistically significant.

Conclusion: It is concluded that stent placement can result in the reduction of frequency of patients who develop acute pancreatitis after ERCP.

Keywords: ERCP, Pancreatitis, Stent