Abstract

Aim: To determine trace elements levels (Zinc, copper and iron) and their correlation in patients with Oculocutaneous albinism (OCA). Methods: Total eighty (80) subjects were selected for this study comprising of 40 healthy controls and 40 cases of OCA. The serum concentrations of trace elements zinc (Zn), copper (Cu) and iron (Fe) were carried out by atomic absorption spectrophotometer. Results: Results showed that the serum Zn and Cu levels were significantly lower in patients (p <0.05) than controls, while no significant difference was observed for serum iron (Fe) levels between patients and controls (p >0.05). Although, there was the reduced concentration of trace elements in patients, but no correlation was established. Conclusion: In conclusion, trace elements (Zn and Cu) were significantly lowered in OCA patients but no correlation was determined with different OCA phenotypes in patients. Keywords Oculocutaneous albinism (OCA), Zn, Cu and Fe, Pakistan.