Abstract

Objective: To determine the role of CRP in determining the extent and severity of coronaryyarteryydisease (CAD).

Methods: This descriptive cross sectional study was conducted in the cardiology department of MMDC and Ibna-Siena Hospital Multan. The samples were collected from January-2020 to October-2020. A total of 100 patients were included in analysis. Patients with diagnosis of acute myocardial infarction who had undergone coronary angiography for the diagnosis and determination of severity of CAD were included in the study. Patients having hs-CRP ≥8.4 mg/L were labelled as having elevated levels.

Results: Mean age was55.8±9.7 years. There were 26% female and 74% male patients. In patients with raised hs-CRP levels, 57 (89.1%) patients had >70% stenosis, while in patients with normal hs-CRP levels, 15 (41.7%) patients had >70% stenosis (p-value 0.0002). Regarding number of diseased vessels, 44 (68.8%) patients with raised hs-CRP had MVD, and only 12 (33.3%) patients with normal hs-CRP had MVD (p-value 0.001). Conclusion: High sensitivity CRP is a valuable test for predicting the extanttandsseverity of CAD.