Pathophysiology Changes in Extraocular Muscles in Thyroid Eye Disease: Ophthalmic and Radiological Correlation in our Population
Tariq Pervaiz Khan, Saad Qayyum, Qumber Abbas, Muhammad Arshad, Zimar Arshad
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Abstract
Objective: To study the effect of thyroid eye disease on extra ocular muscles both clinically and radiologically.
Study Design: Descriptive study
Place and Duration of Study: Department of Ophthalmology, CMH Lahore from 1st January 2019 to 31st December 2019
Methodology: One hundred and ten confirmed cases of thyroid eye disease were included in the study. Visual acuity, intraocular pressure (IOP), extraocular motility, anterior and dilated posterior segment examination were carried out to determine the ophthalmic status. Computed tomography scan and magnetic resonance imaging were done to correlate radiological findings.
Results: Mean age of subject was 43 years. 42 (38.1%) were males and 68 (61.8%) were females. There was orbital fat involvement in 92% of patients and extraocular muscle involvement in up to 89% of patients. There was predominant involvement of inferior and medial rectus muscles.
Conclusion: Thyroid ophthalmopathy is associated with variable morbidity in terms of ocular motility problems and visual loss. Radiological finding correlate well with clinical findings
Key words: Thyroid eye disease, Ophthalmopathy, Exophthalmos, Magnetic resonance imaging, Extraocular muscles