Abstract

Objective: To compare the effectiveness of bromocriptine versus vitex agnus castus ovitex in patients with hyperprolactinemia. Study Design: Randomized Control trial Place & Duration of Study: Department of Obstetrics & Gynaecology, M. Islam Teaching Hospital, Gujranwala from 1st January 2020 to 30th June 2020. Methodology: One hundred patients were included in this study. Patients detailed demographics age, sex and body mass index were recorded after taking written consent. The patients were 20 to 50 years of age. Patients were equally divided into two groups; Groups A (vitex agnus castus ovitex) and the group B (bromociptine). Complete follow up was performed to check prolactin levels. Complications were also observed in this duration. Results: Mean age of the patients in group A was 29.14±4.18 years with body mass index 22.43±8.74 kg/m2 while in group B mean age was 30.02±1.08 years with mean BMI 23.34±4.47 kg/m2 .Difference between both groups was recorded on the basis of prolactin levels. Significantly no difference (p >0.05) was observed regarding prolactin levels in both groups were lower. Frequency of side effects was recorded higher in bromocriptine group as compared to vitex agnus castus ovitex group. Conclusion: Both bromocriptine and vitex agnus castus ovitex were effective but these drugs had some side effects and the frequency of complications was lower in vitex agnus castus ovitex. Keywords: Hyperprolactinemia, Bromocriptine, Vitex agnus castus ovitex