Abstract

Objective: To determine the impact of HbA1c on clinical outcome after coronary artery bypass graft surgery in patients with diabetes mellitus.

Study Design: Randomized control trial.

Place and Duration of study: Department of Cardiac Surgery, Faisalabad Institute of cardiology, Faisalabad from 1st June 2019 to 30th June 2020.

Methodology: Five hundred patients who underwent isolated coronary artery bypass graft surgery were included and stratified into two groups according to HbA1c levels. Control group have patients with HbA1c levels less than 7% while Study group have patients with HbA1c levels greater than 7%. Postoperative atrial fibrillation (AF), myocardial infarction (MI), hospital stay, time on ventilator, stroke, wound infection, in-hospital and 30 day mortality were recorded and compared.

Results: There are statistically significant results in terms of hospital stay, time on ventilator and wound infection (p-value 0.001).

Conclusion: HbA1c is good predictor of in hospital morbidity, so it is necessary to have strict glycaemic control to prevent postoperative complications.

Keywords: Glycosylated haemoglobin, Coronary artery bypass grafting, Diabetes, Myocardial infarction, Wound infection, Stroke, Mortality