Abstract

Objective: To examine the frequency of pre-eclampsia in pregnant women also determine the treatment outcomes.

Study Design: Prospective/Observational

Place and Duration of Study: Department of Obstetrics & Gynecology, Ayesha Hospital, Lahore Cantt from 1st January 2018 to 31st December 2019

Materials and Methods: Four hundred pregnant women with ages 18 to 40 years attending antenatal clinic were enrolled in this study. Patients detailed demographics and medical history were recorded. Systolic BP, diastolic BP and proteinuria were examined. Methyldopa with nifedipine was given to preeclamptic patients. Treatment outcomes were examined.

Results: Severe pre-eclampsia was found in 70 (17.5%) patients. Majority of patients 32 (45.71%) were between 20 to 25 years of age. Mean gestational age of pre-eclamptic patients was 32.15±3.2 weeks. Mean BMI was 20.42±2.48 kg/m2. A significant improvement was observed in term of reducing the systolic blood pressure and diastolic blood pressure after treatment (pre treatment mean systolic blood pressure was 166.3±20.46 mmHg and after treatment it was 142.37±12.75 mmHg with p-value <0.0001). At start mean diastolic blood pressure was 110.42±11.40 mmHg and after treatment it was 92.54±6.28 mmHg with p-value <0.0001.

Conclusion: The frequency of severe pre-eclampsia is very high. The use of methyldopa with nifedipine is safe and effective for the treatment of severe pre-eclampsia.

Key words: Frequency, Severe pre-eclampsia, Outcome