Abstract

Background: Cervical cancer remains one of the single commonestgynecologicalmalignancyamongst women in developing countriesand subsequent afterbreast cancersthrough all age sets.Nevertheless a preventable disease, the death rate is very high because it is an unheededcondition in Pakistan in terms of awareness, screening, follow ups of high risk patients and most importantly, vaccination.

Aim: To highlight the clinico pathological profile of cervical carcinoma in the cervical biopsies and hysterectomy specimens.

Study design: This retrospective surveillance was conducted at a communal Public sector diagnostic and management facilitycenterlocated in Lahore, Pakistan.

Methods: This was a retrospective study to determine the histopathological characteristics of carcinoma of the uteri cervix diagnosed in our center over a 2-year period .1450 cervical specimen were gathered at the hospital during a two year stretch periodcovering November, 2018 to October, 2020. Histological diagnosis were confirmed by qualified fellows of histopathology department, including the author.

Results: Out of 1450 cervical histological findings, 28were cervical carcinomas .Squamous cell carcinoma was the commonest histological sub-type with 62% being moderately differentiated.Commonest age range was 50-70 years.Commonest Clinical presentation included, post-menopausal bleeding per vagina, post-coital bleeding

Conclusion: The findings submit that cervical carcinoma is still an unveiled, yet diagnostically critical among women visiting our hospital to seek medical attention for various conditions of the uterine cervix with squamous cell carcinoma being the most prevalent histological type. Policies that encourage the implementation, monitoring and evaluation, screening and vaccination have to be considered to reduce the affliction of cervical cancer

Keywords: Cervix, Cervical Cancer, Squamous cell carcinoma, HPV, Pakistan