Abstract

Aim: To present our experience in managing hepatitis Ein pregnancy and to find association between maternal mortality and advanced gestational age.

Methods: A total of 10 cases of pregnant females were selected who reported with HEV Ig M positive in tertiary care hospital from Jan 2019 to June 2019. Detailed history and examination were taken and course of disease followed in all ten cases with maternal and foetal outcome.

Results: Mean age of patients at presentation was 25.9 years. Mean gestational age at time of presentation was 30 weeks. Yellow discoloration of sclera was the presenting complaint in 90%of the patients. Five out of ten patients needed ICU admissions and among them 3 needed mechanical ventilation. Maternal mortality was 3 out of total ten patients. All of the patients who expired were in their third trimester. Two patients had intra uterine foetal deaths at time of presentation and there were four early neonatal deaths due to prematurity.

Conclusion: The study showed that pregnant females affected by hepatitis E virus in their third trimester had increased risk of maternal mortality. There is also increased risk of pre term delivery in patients with hepatitis E virus infection.

Keywords: Maternal mortality, Foetal outcome, pre term labour, Hepatic failure