Vitamin D Deficiency and Adverse Results in COVID-19
Maria Mehmood, Zobia Mubarak, Irum Javed, Sarah Arif, Sikandar Ali Khan, Samreen Jan
3499
ABSTRACT
Aim: The goal of this study
is to find out how common vitamin D deficiency is in patients with corona virus
disease and what the consequences are.
Study Design: Observational /Prospective
Place and Duration: Institute of Basic
medical sciences, Khyber Medical University (KMU), Jan 2021-Oct 2021.
Materials &
Methods: This
study included 120 patients of both genders who had been diagnosed
with covid-19. Patients ranged in age from 15 to 75 years. After receiving
written agreement, demographically detailed such as age, sex, and BMI were
recorded. All of the patients had a 5 mL blood sample obtained to check their
vitamin D levels. 25(OH)D < 25 nmol/L (10 ng/dL) was considered severe
Vitamin D insufficiency. The prevalence of vitamin D insufficiency as well as
negative effects were investigated. SPSS 23.0 was used to analyse the data.
Results: The mean age of the
120 patients was 40.11±8.64 years, with 68 (56.7%) males and 52 (43.3%)
females. There were 52 patients (43.3%) with severe vitamin D insufficiency.
There were 17 deaths of the total number of patients in the study. Vitamin D
deficiency was associated with a higher mortality rate in patients with
covid-19 disease than in those who had normal levels of vitamin D, a finding
that was statistically significant at the 0.05 level.
Conclusion: It was found that
severe deficiency of vitamin D and death in individuals with covid-19 illness
had a strong association.
Keywords: Mortality, Vitamin D
Deficiency, Covid-19,