Effects of Clinical Symptoms and Laboratory Values of COVID- 19 Patients' Tests at the Time of Hospitalization on Their Clinical Outcomes
Toomaj Shahverdi, Mahdi Nikoo Hemmat, Mohammad Islamy
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ABSTRACT
Introduction: At the end of 2019, a new coronavirus caused pneumonia in Wuhan, China. Several studies have described the clinical features and immune manifestations in COVID-19 patients with moderate to severe symptoms, while their clinical relevance is less clear. This study investigates the effects of clinical symptoms and laboratory values of COVID-19 patients' tests at the time of hospitalization on their clinical outcomes.
Methodology: This descriptive cross-sectional study was performed on COVID-19 patients hospitalized in Arak hospitals from April 2020 to March 2020. Medical records of all the hospitalized patients were retrieved. Trained personnel extracted general information (age and gender) and clinical profiles (the complete blood count and other required tests).
Findings: Analyzing the laboratory indices of the blood count and LDH and CPK levels revealed a positive relationship between the patients' serum CPK levels, and the mortality rate (P = 0.001) and length of hospitalization (P = 0.015).
Conclusion: The patients' serum LDH levels and fever were also associated with the mortality rate, and the need for mechanical ventilation, respectively. We hope this information helps physicians treat COVID-19 patients.
Keywords: COVID-19, clinical symptoms, laboratory tests