ABSTRACT

The regeneration of a periodontal tissues based on the viability of the productive cells, Essential paradigm in periodontal heath keeping and cure after surgical therapy is the regeneration of the attachment apparatus. Predictable periodontal regeneration following periodontal surgery is a major goal of therapy. Surgery aimed to create a new attachment or re-attachment of their apparatus. The aim of this study is to test the benefits of tissucol and stem cell activation to restore the periodontal apparatus with the application of the innovative surgical procedure that deal with the application of the biological glue in addition to the activation of the local stem cell. published as part1 of study in 2019. Forty-two patients have been incorporated in this study, twenty-one females and twenty on male, aged from 16 years old up to 55 years, subdivided in two groups. They were examined clinically and radiologically. All have chronic periodontitis, moderate or severe, with pocket depth ranged from 4 to 10 mm, the surgical procedure applied activates the local stem cells with assistance of tissucol as adhesive and hemostats. results showed, probing depth showed a significant decrease in depth, the probing depth and attachment level showed a significant reduction (P<0.05). Statistical compares in variance between data of first group and second showed that the baseline records were significantly indifferent, while the postoperative records showed a significant (P<0.05) variations in privilege to the first group (tissucol). In conclusion; Our results could be related, firstly, to a reasonable surgical procedure, the enhancement of tissue regeneration, endosteal cell activation and a rapid hemostasis with thin blood clot formation that could impeach an epithelial invasion.

Keywords: surgery, innovative technique, biologic glue, tissucol, regeneration, pocket reduction, periodontal pockets.