Aim: Association between smoking and periodontal disease with sociodemographic profile and different levels of oral hygiene status.

Study Design: Case control study.

Place and Duration of Study: Khyber College of Dentistry and Sardar Begum Dental College and Hospital Peshawar KPK from 1st July 2020 to 31st December 2020.

Methodology: The were 300 patient from 20-50 years of age were enrolled in the study. The sample was stratified into two groups, cases and controls150 patients in each group. Patients were clinically evaluated by measuring the PDI scores and oral hygiene index.

Results: There were (43.3%) smokers and (56.6%) were non-smokers. There were 57.3% smokers and 42.6% were non-smokers with periodontal disease the result was significant (p=0.0001), while 29.3% smokers and 70.6% were non-smokers and did not have periodontal disease. The oral hygiene status was poor among smokers it was 23.1% while 2.9% among non-smokers, with significant result p-value was =0.0001. There was an association between periodontal disease with different levels of smoking the result was significant (p=0.0001).

Conclusions: There was an association between smoking, sociodemographic profile with periodontal disease and oral hygiene status.

Keywords: Periodontal disease, Smokers, Non-smokers, Periodontal disease index, Oral hygiene index