Introduction: The disease burden of Chronic Kidney Disease (CKD) is increasing every day and adding the burden on our healthcare system. Many patients are being treated by hemodialysis due to a very limited recourses available. Cardiovascular complications such as ischemic heart disease (IHD) are very common in patients who are being treated by hemodialysis and one of the leading causes of death in these patients.

Objective: Frequency of IHD in the patients of ESRD.

Methodology: Cross-sectional type of study was piloted for duration of three months from April 2019 to June 2019 in Nephrology Department Mayo Hospital Lahore. Eighty one patients were recruited who fulfilled the inclusion criteria i.e. patients suffering end stage renal disease on maintenance hemodialysis through non-probability, convenient sampling. A standard questionnaire was used to collect the data. All the data was analyzed by using SPSS (software package for statistical analysis) version 20.

Results: The study was carried out among 81 patients with diagnosis of Chronic Kidney Disease on the maintenance hemodialysis. Most patients in study were falling in the range of 21-60 years. The study included 46 (56.8%) males and 35(43.2%) females. The frequency of Ischemic Heart Diseases in these patients was found to be 56.8% (46/81 cases).

Conclusion: Both genders are equally affected. The frequency of IHD in patients of end stage renal disease who are on hemodialysis is observed to be high, but not as much high as observed in previous studies. Both genders are affected almost equally.

Key Words: Ischemic Heart Disease, End stage renal disease, chronic kidney disease, Hemodialysis.